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Yeast Genome > Codon Bias Index (CBI)

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Codon Bias Index (CBI) Defined

Codon bias index is another measure of directional codon bias, it measures the extent to which a gene uses a subset of optimal codons. CBI is similar to Fop, with expected usage used as a scaling factor. In a gene with extreme codon bias, CBI will equal 1.0, in a gene with random codon usage CBI will equal 0.0. Note that it is possible for the number of optimal codons to be less than expected by random change. This results in a negative value for CBI. [Bennetzen, J. L., and B. D. Hall , (1982). Codon selection in yeast. Journal of Biological Chemistry 257: 3026-3031. Abstract]

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