The following information is about Epistasis.

Epistasis Defined

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Off-site Epistasis Links, User Submitted

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Tue Jun 23

• http://compgen .blogspot.com/

Thu Mar 12

• Focused Interaction Testing Framework (FITF) Software: It is designed for case-control studies involving diallelic candidate genes. A full description of the method can be found in the following article: Joshua Millstein, David V. Conti, Frank D. Gilliland, W. James Gauderman. A testing framework for identifying susceptibility genes in the presence of epistasis. (not yet available -- in review)
• Computational Genetics Laboratory at Dartmouth Medical School: Welcome to the homepage of the Computational Genetics Laboratory at the Norris-Cotton Cancer Center and Dartmouth Medical School in Lebanon, New Hampshire. Our mission is to improve the prediction, prevention, and treatment of common human diseases such as cancers, cardiovascular diseases, and psychiatric diseases through the development, evaluation, and application of statistical and computational methods for genetic, genomic, proteomic and metabolomic analysis. Our focus is on methods and software that embrace, rather than ignore, the hierarchical nature and complexity of disease initiation and progression. Epistasis, or gene-gene interaction, is one such complicating factor.
• epistasis blog - MDR posts: Blog posts about Multidimension ality reduction software
• mdr: MDR is a data mining strategy for detecting and characterizing nonlinear interactions among discrete attributes (e.g. SNPs, smoking, gender, etc.) that are predictive of a discrete outcome (e.g. case-control status). The MDR software combines attribute selection, attribute construction and classification with cross-validati on to provide a powerful approach to modeling interactions.

Thu Dec 18

• Mendelian Genetics: epistasis pleiotropy other mendelian genetics

Mon Nov 10

• Systematic Interpretation of Genetic Interactions using Protein Networks

Fri Oct 31

• Gene Expression: Jim Manzi on epistasis

Mon Oct 20

• Epistasis [mdash] the essential role of gene interactions in the structure and evolution of genetic systems : Abstract : Nature Reviews Genetics: Epistasis is a bit confusing word. The author proposed three epistasis: functional, compositional, and statistical epistasis.

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Off-site Epistasis Research Links

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