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Yeast Genome > Exon
The following information is about Exon.
Exon Defined
A portion of a split gene that is included in the transcript of a gene and survives processing of the RNA to become part of the spliced messenger of a structural RNA. Exons generally occupy three distinct regions of genes that encode proteins. Exons in the first region are not translated into protein, but signal the beginning of RNA transcription and contain sequences that direct the mRNA to ribosomes for protein synthesis. Exons in the second region contain the information that is translated into the amino acid sequence of the protein, and are sometimes referred to as coding exons. Exons in the third region are transcribed into the part of the mRNA that contains the signals for the termination of translation and for the addition of a polyadenylate tail.
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Off-site Exon Links, User Submitted
The following links have been collected through user bookmark submission in the Exon category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
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- Technology Review: Fixing a Genetic Flaw: An international team of researchers has successfully treated dogs with the canine form of Duchenne muscular dystrophy (DMD), a rapidly progressing and ultimately fatal muscle disease that afflicts one out of every 3,600 boys. The researchers used a novel technique called exon skipping to restore partial function to the gene involved in Duchenne. The study, published in Annals of Neurology, gives hope that a similar approach could work in humans.
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- Differential chromatin marking of introns and expressed exons by H3K36me3 : Abstract : Nature Genetics: exons are preferentially marked with H3K36me3 relative to introns. H3K36me3 exon marking is dependent on transcription and is found at lower levels in alternatively spliced exons, supporting a splicing-relat ed marking mechanism. We further show that the difference in H3K36me3 marking between exons and introns is evolutionarily conserved in human and mouse. We propose that H3K36me3 exon marking in chromatin provides a dynamic link between transcription and splicing.
- Processing the H3K36me3 signature : Abstract : Nature Genetics: A study in Caenorhabditis elegans now shows that nucleosomes covering exons and introns on active genes are differentially marked by H3K36 trimethylation , suggesting a new mode of communication between chromatin and pre-mRNA processing.
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If you would like to find additional social bookmark based links on the topic of we recommend the Open Tag Directory > Exon. If you would like to find related tags we recommend Tag Patterns > Exon
Off-site Exon Research Links
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