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Yeast Genome > Frequency Of Optimal Codons (Fop)

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Frequency Of Optimal Codons (Fop) Defined

This index is the ratio of optimal codons to synonymous codons (genetic code dependent). Fop values for the original index are always between 0 (where no optimal codons are used) and 1 (where only optimal codons are used). When calculating the modified Fop index, negative values are adjusted to zero. [Ikemura, T. (1981). Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli system. Journal of Molecular Biology 151: 389-409.]

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