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Yeast Genome > UORF
The following information is about uORF.
uORF Defined
Small upstream open reading frame (uORF) that precedes the major open reading frame (ORF). uORFs usually inhibit downstream translation by blocking ribosomal scanning to promote efficient termination. In some cases, uORFs stimulate translation of the major ORF by allowing scanning ribosomal subunits to proceed via leaky scanning and reinitiation to the major ORF.
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